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Six-eight piperazine is professionally provided by our company for consumers. In addition, there are many things to watch for how to make N-methylpiperazine from six-eight piperazine. Let’s take a look. How to make N-methylpiperazine from six eight piperazine What are the wide uses of six eight piperazine in various industries?"

【Preferred】How to make N-methylpiperazine from hexaoctapiperazine What are the wide uses of hexaoctapiperazine in various industries

N-methylpiperazine is used in the preparation of antibacterial drugs meperifamycin, antipsychotics trifluoperazine and ofloxacin, etc., and it is seriously used as ofloxacin, clozapine, sildenafil It can also be used in pesticides, dyes, plastics and other occupations.

is derived from the methylation of hexa-octapiperazine. Put six-eight piperazine and hydrochloric acid in an answering pot, heat to 45°C, and add dropwise a mixture of formic acid and formaldehyde. After the addition, answer the sound at about 50°C for 2-3 hours, and then increase the temperature to reflux until the carbon dioxide gas no longer escapes and stops. Cool to 80°C, add hydrochloric acid, heat and distill the acid to dryness. Participate in methanol after being cooled slightly, heat to reflux for 30 min, and filter while hot (the filter residue is piperazine dihydrochloride). The filtrate uses methanol to the end, and the residue is added to the sodium hydroxide solution to pH=14, and distilled to obtain aqueous methyl piperazine. Add benzene and heat to reflux with water until it is exhausted. Fractional distillation, network 132-140 ℃ distillate six eight piperazine, six eight piperazine to make N-methyl piperazine how to make anhydrous methyl piperazine. The yield is about 50%.

More similar articles: Anhydrous Piperazine Introduction Card

Six-eight piperazine has a certain effect in various occupations. In the surfactant industry, the hydrogen atom on the amino group of the piperazine molecule is replaced by a long-chain alkyl or alkoxy derivative. It can be used as a wetting agent and emulsifier. , Dispersant and detergent. In the field of synthetic resins, polymers containing piperazine monomers have many common functions, such as increasing the melting point of products and improving their solubility. Resins and synthetic fibers containing such polymers can be used in a variety of special applications. In the printing and dyeing industry, piperazine and 1,4-diarylpiperazine are used in the synthesis of dyes to prevent the fading of printed and dyed fabrics. In the rubber industry, the reaction product of piperazine with formaldehyde and carbon disulfide can be used as a rubber vulcanization accelerator and directly used to vulcanize halogen synthetic rubber.

In addition, piperazine or alkyl can be used as corrosion inhibitor instead of piperazine and ethylene glycol aqueous solution; some derivatives of piperazine can be used as additives in hydraulic transmission fluid and engine freezing fluid; dialkylphenol and hexa-octapiperazine What are the wide uses of piperazine in various industries? The azine and formaldehyde condensates can be used as stabilizers for polyolefin lubricating oils; monoesters of N,N'-dihydroxyalkylpiperazine and various fatty acids can be used to improve fatty acid soaps Additives with anti-hard water function; N,N'-Dihydroxyethylpiperazine monoester and monoether can be used as emulsifiers in cosmetics.

Okay, about "How to make N-methylpiperazine from hexa-octapiperazine and what are the wide-ranging uses of hexa-octapiperazine in various industries", let’s talk about it today. If you have any questions, or for There are other things you want to know about piperazine, piperazine, etc., you can consult by phone, of course, you can also consult our customer service online!

Keywords in this article: hexa-octapiperazine, hexa-octapiperazine, used as methyl, participated in heating